Evolysse® Collection of Dermal Fillers

The Evolysse® collection is a next-generation line of injectable dermal fillers designed to restore volume, smooth wrinkles, and enhance natural facial contours. Developed by Evolus, this collection uses advanced hyaluronic acid (HA) technology to deliver results that look and feel more natural than traditional fillers.

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What Makes Evolysse® Different?

Unlike conventional fillers, Evolysse® is formulated using proprietary Cold-X™ Technology, a unique manufacturing process that preserves the natural structure of hyaluronic acid. This allows the filler to integrate more seamlessly into the skin, providing a softer, more natural appearance and movement with facial expressions.

Key benefits include:

  • Natural look and feel
  • Smooth integration into facial tissue
  • Long-lasting hydration and volume
  • Minimal downtime after treatment

The Evolysse® Filler Line

The Evolysse® collection currently includes two specialized fillers, each designed for different aesthetic needs:

Evolysse® Form

Evolysse® Form is a firmer, more structured filler ideal for deep contouring and facial support. It is commonly used to enhance areas such as:

  • Cheeks
  • Jawline
  • Chin

This formulation helps restore facial structure and provides a lifted, sculpted appearance.


Evolysse® Smooth

Evolysse® Smooth is a softer, more flexible gel designed for fine lines and subtle volume enhancement. It is best suited for:

  • Smile lines (nasolabial folds)
  • Lips and perioral lines
  • Delicate facial areas

It delivers a refined, natural-looking result while maintaining facial softness and expression.


What Can Evolysse® Treat?

Evolysse® fillers are FDA-approved to treat moderate to severe facial wrinkles and folds, particularly dynamic areas such as smile and laugh lines.

They can also be used to:

  • Restore lost facial volume
  • Improve symmetry and balance
  • Enhance natural contours
  • Address changes from aging or weight loss

Results and Longevity

Patients can expect immediate improvement in treated areas, with results that continue to refine as the filler settles. Depending on the product and treatment area, results typically last 6 to 12 months or longer.


A Modern Approach to Natural Beauty

The Evolysse® collection represents a shift toward subtle, natural-looking aesthetic enhancements. By preserving the integrity of hyaluronic acid and tailoring formulations for specific concerns, Evolysse® offers a versatile solution for full-face rejuvenation—without the overfilled look.